Bone Biomaterial is a flowable, moldable paste that can conform to and interdigitate with the host bone. It rapidly hardens itself in vivo and in the presence of serum, forming a solid bone-like structure capable of stabilizing fractured bone within five to 15 minutes. Bone Biomaterial is also useful as a bone substitute, eliminating the need for autologous or allogenic bone grafts. Because it is moldable, it may be used to manufacture resorbable orthopedic hardware such as intermedullary nails, screws and plates. The technology has superior compressive strength, due to the use of nano-particle technology, allowing it to be used for both weight bearing and non-weight bearing bones as opposed to currently marketed bone cement products that are only recommended for non-weight bearing bones. Other known calcium phosphate based formulations have inferior compressive strength to our technology.

The invention resists disintegrative washout upon contact with blood, and injection into the wound is less stressful to surrounding tissue, and completely biocompatible with the physiological environment. Todays most popular bone cements, which contain PMMA (polymethylmethacrylate), were recently determined to be linked to numerous serious side effects, including tissue damage and nerve root pain associated with percutaneous vertebroplasty and kyphoplasty procedures, as indicated by the FDA in a November 2002 warning notice.

The chemical composition and physical architecture of this biomaterial is highly compatible with supporting chondrocyte growth, and testing has demonstrated that the biomaterial can be resorbed by living chondrocyte. Test results suggest that the biomaterial will be resorbed and replaced in the body. More particularly, chondrocyte can be expected to grow to make bone and cartilage-like biomaterial.