Drug Delivery Compounds

This technology provides a means of administering drugs to a targeted site via novel compounds. These novel compounds include a variety of therapeutics linked to polysaccharides, from which they can be slowly released when placed in the body. They are prepared by a unique method from carboxy- and carboxymethylpolysaccharides, which when coupled to the therapeutics result in products essentially free of contaminating and potentially toxic coupling agents. Moreover, they are water soluble and can be prepared as a gel, thus offering a variety of options in administering therapuetics, which include implanted as strips, ribbons, or films, or by direct injection.

Thus, these compounds may dramatically improve the control and effectiveness of administered therapeutics, and are expected to find use in treating a variety of medical conditions ranging from cancer to abdominal adhesions; for example, they are believed to be uniquely suitable for the treatment of ovarian cancer. Examples of therapeutics include amino and hydroxy containing chemotherapeutics such as cisplatin, aminoglutheimide, mitoxantrone, finasteride, aminoglutheimide, and mitoxantrone. The compounds are not limited to therapeutics, as other bioactive molecules such as flavorants may also be linked to the polysaccharides.

For more information about this patent pending technology and for licensing opportunities, please contact:

Girish Nallur, Ph.D.
Chief Scientific Officer
Competitive Technologies, Inc.
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Tel: 203.368.6044